2-chloro-4-Bromo-5-methylpyridine

Specification: Enterprise standard
CAS: 867279-13-8

 

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Basic Information

Product Name: 2-Chloro-4-bromo-5-methylpyridine

Chinese Name: 2-氯-4-溴-5-甲基吡啶

Molecular Formula: C₆H₅BrClN

Molecular Weight: 206.47 g/mol

Structure: This compound is a halogenated pyridine derivative with a chlorine atom at the 2-position, a bromine atom at the 4-position, and a methyl group at the 5-position on the pyridine ring.


2-Chloro-4-bromo-5-methylpyridine is a versatile heteroaromatic compound commonly used as an intermediate in organic synthesis. The presence of two halogen atoms enables stepwise or selective substitution, coupling, and derivatization reactions. Its electron-deficient pyridine ring structure is useful in the preparation of pharmaceuticals, agrochemicals, and functional materials.

 

Main Uses

Intermediate in the synthesis of active pharmaceutical ingredients and crop protection agents.

Building block in heterocyclic chemistry and combinatorial synthesis.

Precursor for functionalized pyridine derivatives in material and coordination chemistry.

 

Typical Applications

Used in cross-coupling reactions (e.g., Suzuki, Buchwald–Hartwig) to introduce various functional groups.

Starting material for selective halogen exchange or nucleophilic substitution reactions.

 

Applied in the preparation of advanced heterocyclic scaffolds for drug discovery.