2-chloro-4-(2,2-dimethylpropyl)pyridine

Specification: Enterprise standard
CAS: 2387538-18-1

 

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Basic Information

Product Name: 2-Chloro-4-(2,2-dimethylpropyl)pyridine

Chinese Name: 2-氯-4-(2,2-二甲基丙基)吡啶

Molecular Formula: C₁₀H₁₄ClN

Molecular Weight: 183.68 g/mol

Structure: This compound features a pyridine ring substituted with a chlorine atom at the 2-position and a branched alkyl group (2,2-dimethylpropyl, also known as neopentyl) at the 4-position.


2-Chloro-4-(2,2-dimethylpropyl)pyridine is a substituted pyridine derivative used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The chloro group on the heteroaromatic ring offers a reactive site for nucleophilic substitution or metal-catalyzed coupling, while the bulky alkyl chain affects steric properties and lipophilicity of downstream molecules.

 

Main Uses

Intermediate in the synthesis of agrochemicals, such as herbicides or insecticides.

Used in pharmaceutical development for heterocyclic compound synthesis.

Serves as a precursor for functional pyridine derivatives in chemical research.

 

Typical Applications

Participates in metal-catalyzed cross-coupling reactions at the chloro position.

Used to develop pyridine-based scaffolds with altered hydrophobicity.

 

Can undergo substitution to introduce various nucleophiles on the pyridine ring.