2-Bromo-1-chloro-3-fluoro-4-methylbenzene

Specification: Enterprise standard
CAS: 1402667-29-1

 

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Basic Information

Product Name: 2-Bromo-1-chloro-3-fluoro-4-methylbenzene

Chinese Name: 2-溴-1-氯-3-氟-4-甲基苯

Molecular Formula: C₇H₅BrClF

Molecular Weight: 223.47 g/mol

Structure: This compound is a halogenated methylbenzene derivative, featuring a bromine atom at the 2-position, chlorine at the 1-position, fluorine at the 3-position, and a methyl group at the 4-position of the aromatic ring.


2-Bromo-1-chloro-3-fluoro-4-methylbenzene is a multi-substituted aromatic compound frequently used as an intermediate in organic synthesis. The presence of three different halogens allows for selective functionalization and stepwise derivatization, which is valuable in the development of pharmaceuticals, agrochemicals, and specialty chemicals.

 

Main Uses

Intermediate in the synthesis of halogenated aromatic compounds.

Raw material for pharmaceutical and agrochemical development.

Precursor for functionalized aromatic building blocks in material chemistry.

 

Typical Applications

Participates in cross-coupling reactions (e.g., Suzuki, Sonogashira) via the bromine or chlorine sites.

Starting point for further halogen exchange or nucleophilic aromatic substitution.

 

Used in the design of fluorinated and halogenated compound libraries for screening or materials research.