Basic Information
Product name: 1,3-Dibromo-5-tert-butylbenzene
Chinese name: 1,3-二溴-5-叔丁基苯
Molecular Formula: C10H12Br2
Molecular weight: 292.01 g/mol
Structure: This is a compound with two bromine (Br) atoms and a tert-butyl group attached to the benzene ring.
1,3-Dibromo-5-tert-butylbenzene is a benzene ring derivative with two bromine substituents and a bulky tert-butyl side chain. It can be thought of as an aromatic halogenated hydrocarbon.
Main Uses
Pharmaceutical intermediates
- It is often used as an intermediate in pharmaceutical synthesis, especially in the synthesis of certain complex aromatic drug molecules, as a raw material for building aromatic core structures. Because it has two bromine atoms, this compound is well suited to participate in coupling reactions such as Suzuki, Stille, Heck, etc., and is used to further introduce complex substituents.
Raw material for organic synthesis
- Because it has two reactive bromine sites, it is an excellent difunctional building block, and can be used to synthesize polymers, organic materials, liquid crystal monomers, etc.
Functional material development
- In the development of certain high-performance materials (such as OLED light-emitting materials, liquid crystal display materials), it can be used as one of the precursors of the aromatic skeleton.
Typical Applications
Suzuki Coupling
Reacts with boronic acid or boronic esters to build C-C bonds and introduce different substituents.
Grignard Reaction
The bromine position can be reacted with magnesium metal to form Grignard reagents for subsequent organic synthesis.
